Category: Medications
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FDA Approves Reformulated Ranitidine Following Comprehensive Safety Review
The U.S. Food and Drug Administration (FDA) has approved a reformulated ranitidine tablet after a comprehensive safety review addressing prior concerns about N‑nitrosodimethylamine (NDMA) impurity formation; the approval includes updated storage and handling requirements to mitigate impurity risk and preserve product stability. Background and regulatory context Ranitidine, an H2‑receptor antagonist widely used for gastroesophageal reflux…
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The Price Paradox: Why Your Prescription Costs 278% More Than the Same Pill Abroad
The United States leads the world in pharmaceutical innovation, developing life-saving therapies that benefit global health. Yet, a striking paradox exists: Americans pay significantly more for prescription drugs than consumers in virtually every other high-income country. This disparity isn’t a minor difference; it’s a chasm, rooted in fundamental differences in how the U.S. and its…
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FDA Approves Ziftomenib for Acute Myeloid Leukemia
The treatment landscape for acute myeloid leukemia (AML) has recently seen a significant development with the U.S. Food and Drug Administration (FDA) granting full approval to ziftomenib (Komzifti™) for adult patients diagnosed with relapsed or refractory (R/R) AML who harbor a susceptible NPM1 (Nucleophosmin 1) mutation and have no satisfactory alternative treatment options. This landmark…
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Breakthrough Cancer Drug With No Detectable Side Effects
A significant nanomedicine breakthrough from Northwestern University, led by Prof. Chad A. Mirkin and documented in the peer-reviewed journal ACS Nano, details the transformation of the chemotherapy agent 5-fluorouracil (5-Fu) into a spherical nucleic acid (SNA) structure. According to both the article and surrounding scientific coverage, this innovation reports unprecedented increases in cancer cell targeting…
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Managing Chemotherapy Side Effects with Clinical and Lifestyle Interventions
Best Practices for Managing Chemotherapy Side Effects Chemotherapy remains a cornerstone of modern oncology, offering improved survival and the possibility of cure for many types of cancer. Yet for most patients, chemotherapy is synonymous with a daunting array of side effects – nausea, fatigue, mucositis, neuropathy, immunosuppression, and others – that can compromise quality of…
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A Second Opinion on medications: why a data-driven review matters
Every year millions of people begin new prescriptions without a formal, evidence-based second opinion. That single decision can affect treatment effectiveness, quality of life, risk of adverse events, and out-of-pocket cost. A science-based second opinion on medications combines personalized clinical evidence, drug-safety data, and cost information to reduce harms and improve outcomes. This article explains…
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Proper Drug and Medication Disposal: Protecting People, Water, and Wildlife
Improper disposal of unused and expired medicines is a hidden environmental and public-health crisis. Millions of households, clinics, and long-term care facilities discard pharmaceuticals in ways that allow active drug ingredients to enter landfills, septic systems, wastewater treatment plants, and surface waters. These pathways spread bioactive chemicals into ecosystems, contribute to antimicrobial resistance, and increase…
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Biosimilars, Generics, and the New Cost-Control Countertrend in Pharmaceuticals
Prescription drug prices have long been a primary concern for patients, payers, and policymakers worldwide. In recent years, the surge of biosimilars and generics has emerged as a leading force in reshaping the economics of the pharmaceutical industry, promising not only reduced costs but also greater competition and accessibility. As of 2025, this movement —…
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ADRIANA Pain Medication – A Promising Future Alternative to Opioids
The opioid crisis has devastated communities worldwide, particularly in the United States, where opioid overdoses claimed more than 80,000 lives in 2023 alone.¹ While opioids like morphine and oxycodone remain powerful tools for managing severe pain, their risks —including addiction, overdose, and long-term dependence — have created an urgent need for safer alternatives. Enter ADRIANA…
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Fact-Checking Trump’s Autism Drug: Is Leucovorin a Breakthrough or Hype?
Leucovorin for Autism: Clinical Efficacy and Biochemical Mechanisms Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition, affecting communication, social interaction, and behavior, with rising global prevalence and substantial lifelong impact on families and public health systems.1 2 Despite decades of research, interventions addressing the core symptoms-language deficits, social challenges, and repetitive behaviors-remain limited. Leucovorin,…